Early and progressive hydroxychloroquin retinal toxicity: 9-year follow-up with multimodal retinal imaging

Retinopathy secondary to the use of hydroxychloroquine sulfate can cause irreversible central visual loss and progress even after stopping drug. The pathophysiological mechanism by which this phenomenon occurs is unclear. Periodic eye exams associated with multimodal imaging help in early recognition pathology, being essential for realization an diagnosis order minimize adverse sequelae. Patients must be aware risk toxicity its possible consequences, so medication well-founded. Detecting subtle changes perception damage, but not necessarily prevent it. Medications should discontinued, if possible, when recognized or strongly suspected, a decision made together patients their physicians, as it indicated underlying pathological condition that also lead sequelae patients.